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Chinese hamster ovary cell population density affects intracellular concentrations of calcium-dependent regulator and ability of regulator to inhibit adenylate cyclase activity

The adenylate cyclase activity [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] of crude Chinese hamster ovary cell membranes was inhibited 30-40% by low concentrations (6-600 ng/ml) of calcium-dependent regulator (CDR). This inhibitory effect was lost at concentrations of CDR above 600 ng/ml. The...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Evain, Daniele, Klee, Claude, Anderson, Wayne B.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1979
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383956/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/226991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.8.3962
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