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Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia.

Heme oxygenase (HO) catalyzes the rate-limiting step in the degradation of heme to biliverdin, which is reduced by biliverdin reductase to bilirubin. Heme oxygenase-1 (HO-1) is inducible not only by its heme substrate, but also by a variety of agents causing oxidative stress. Although much is known...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Lee, P J, Alam, J, Wiegand, G W, Choi, A M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1996
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38395/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816811/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.19.10393
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