Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells

When vertebrate cells exit mitosis various cellular structures are re-organized to build functional interphase cells(1). This depends on Cdk1 (cyclin dependent kinase 1) inactivation and subsequent dephosphorylation of its substrates(2–4). Members of the protein phosphatase 1 and 2A (PP1 and PP2A) f...

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Main Authors: Schmitz, Michael H. A., Held, Michael, Janssens, Veerle, Hutchins, James R. A., Hudecz, Otto, Ivanova, Elitsa, Goris, Jozef, Trinkle-Mulcahy, Laura, Lamond, Angus I., Poser, Ina, Hyman, Anthony A., Mechtler, Karl, Peters, Jan-Michael, Gerlich, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839080/
https://ncbi.nlm.nih.gov/pubmed/20711181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2092
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