Interrupting the early region of polyoma virus DNA enhances tumorigenicity.

The tumorigenicity of DNA from polyoma virus after cleavage with a variety of restriction enzymes was evaluated in suckling hamsters. Cleavage with enzymes that interrupt the region of the genome coding for the large tumor (T) antigen of polyoma virus markedly enhanced the tumorigenicity above that...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Israel, M A, Simmons, D T, Hourihan, S L, Rowe, W P, Martin, M A
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1979
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/226975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.8.3713
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