Interrupting the early region of polyoma virus DNA enhances tumorigenicity.

The tumorigenicity of DNA from polyoma virus after cleavage with a variety of restriction enzymes was evaluated in suckling hamsters. Cleavage with enzymes that interrupt the region of the genome coding for the large tumor (T) antigen of polyoma virus markedly enhanced the tumorigenicity above that...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Israel, M A, Simmons, D T, Hourihan, S L, Rowe, W P, Martin, M A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1979
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/226975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.8.3713
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