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MHC Class II Protein Turnover In vivo and Its Relevance for Autoimmunity in Non-Obese Diabetic Mice

Major histocompatibility complex class II (MHCII) proteins are loaded with endosomal peptides and reside at the surface of antigen-presenting cells (APCs) for a time before being degraded. In vitro, MHCII protein levels and turnover are affected by peptide loading and by rates of ubiquitin-dependent...

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Detalhes bibliográficos
Main Authors: De Riva, Alessandra, Busch, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839011/
https://ncbi.nlm.nih.gov/pubmed/24324466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00399
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