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Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumorigenesis
Mice lacking c-fos develop osteopetrosis due to a block in osteoclast differentiation. Carboxy-terminal phosphorylation of Fos on serine 374 by ERK1/2 and serine 362 by RSK1/2 regulates Fos stability and transactivation potential in vitro. To assess the physiological relevance of Fos phosphorylation...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838948/ https://ncbi.nlm.nih.gov/pubmed/21119595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.542 |
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