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Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo

The apical junctional complex (AJC), composed of tight and adherens junctions, maintains epithelial barrier function. Since cigarette smoking and chronic obstructive pulmonary disease (COPD), the major smoking-induced disease, are associated with increased lung epithelial permeability, we hypothesiz...

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Autores principales: Shaykhiev, Renat, Otaki, Fouad, Bonsu, Prince, Dang, David T., Teater, Matthew, Strulovici-Barel, Yael, Salit, Jacqueline, Harvey, Ben-Gary, Crystal, Ronald G.
Formato: Artigo
Lenguaje:Inglês
Publicado: SP Birkhäuser Verlag Basel 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838912/
https://ncbi.nlm.nih.gov/pubmed/20820852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0500-x
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