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Cancer Cells Incorporate and Remodel Exogenous Palmitate into Structural and Oncogenic Signaling Lipids

De novo lipogenesis is considered the primary source of fatty acids for lipid synthesis in cancer cells, even in the presence of exogenous fatty acids. Here, we have used an isotopic fatty acid labeling strategy coupled with metabolomic profiling platforms to comprehensively map palmitic acid incorp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Louie, Sharon M., Roberts, Lindsay S., Mulvihill, Melinda M., Luo, Kunxin, Nomura, Daniel K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838875/
https://ncbi.nlm.nih.gov/pubmed/23872477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2013.07.008
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