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Potent Inhibition of the C-P Lyase Nucleosidase PhnI by ImmucillinA-Triphosphate
The C-P lyase complex in bacteria catalyzes the transformation of phosphonates to orthophosphate under conditions of phosphate starvation. The first committed step in the C-P lyase catalyzed reaction is the displacement of adenine from MgATP by phosphonate substrates to yield ribose-1-phosphonate-5-...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838859/ https://ncbi.nlm.nih.gov/pubmed/24111876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4013287 |
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