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Interplay between Velocity and Travel Distance of Kinesin-based Transport in the Presence of Tau

Although the disease-relevant microtubule-associated protein tau is known to severely inhibit kinesin-based transport in vitro, the potential mechanisms for reversing this detrimental effect to maintain healthy transport in cells remain unknown. Here we report the unambiguous upregulation of multipl...

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Detalhes bibliográficos
Main Authors: Xu, Jing, King, Stephen J., Lapierre-Landry, Maryse, Nemec, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838731/
https://ncbi.nlm.nih.gov/pubmed/24268156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.10.006
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