Developmental lineage priming in Dictyostelium by heterogeneous Ras activation

In cell culture, genetically identical cells often exhibit heterogeneous behavior, with only ‘lineage primed’ cells responding to differentiation inducing signals. It has recently been proposed that such heterogeneity exists during normal embryonic development to allow position independent patternin...

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Bibliografiske detaljer
Main Authors: Chattwood, Alex, Nagayama, Koki, Bolourani, Parvin, Harkin, Lauren, Kamjoo, Marzieh, Weeks, Gerald, Thompson, Christopher RL
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2013
Fag:
Developmental Biology and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838634/
https://ncbi.nlm.nih.gov/pubmed/24282234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01067
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