Determinants of RasC Specificity during Dictyostelium Aggregation

RasC is required for optimum activation of adenylyl cyclase A and for aggregate stream formation during the early differentiation of Dictyostelium discoideum. RasG is unable to substitute for this requirement despite its sequence similarity to RasC. A critical question is which amino acids in RasC a...

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Bibliografiske detaljer
Main Authors: Bolourani, Parvin, Spiegelman, George, Weeks, Gerald
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009863/
https://ncbi.nlm.nih.gov/pubmed/20971846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.181115
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