RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation
Disruption of Dictyostelium rasC, encoding a Ras subfamily protein, generated cells incapable of aggregation. While rasC expression is enriched in a cell type-specific manner during post-aggregative development, the defect in rasC(–) cells is restricted to aggregation and fully corrected by applicat...
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| Udgivet i: | EMBO J |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125575/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11500376/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.16.4490 |
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