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RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation

Disruption of Dictyostelium rasC, encoding a Ras subfamily protein, generated cells incapable of aggregation. While rasC expression is enriched in a cell type-specific manner during post-aggregative development, the defect in rasC(–) cells is restricted to aggregation and fully corrected by applicat...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Lim, Chinten James, Spiegelman, George B., Weeks, Gerald
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125575/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11500376/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.16.4490
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