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RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation
Disruption of Dictyostelium rasC, encoding a Ras subfamily protein, generated cells incapable of aggregation. While rasC expression is enriched in a cell type-specific manner during post-aggregative development, the defect in rasC(–) cells is restricted to aggregation and fully corrected by applicat...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125575/ https://ncbi.nlm.nih.gov/pubmed/11500376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.16.4490 |
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