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In vitro protein binding of liraglutide in human plasma determined by reiterated stepwise equilibrium dialysis
Liraglutide is a human glucagon-like peptide-1 (GLP-1) analogue approved for the treatment of type 2 diabetes. It is based on human GLP-1 with the addition of a 16-carbon fatty acid, which facilitates binding to plasma proteins, thus prolonging the elimination half-life and allowing once-daily admin...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley Subscription Services, Inc., A Wiley Company
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838623/ https://ncbi.nlm.nih.gov/pubmed/23853127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23648 |
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