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Lovastatin Dose-Dependently Potentiates the Pro-inflammatory Activity of Lipopolysaccharide Both In Vitro and In Vivo

Since contradictory findings have been reported on potential effects of statins in modulating the inflammatory response, we have analysed the biological activity of lovastatin both in vitro using the Raw 264.7 murine macrophagic cell line and in vivo using BALB/c mice. When added to Raw 264.7 cells...

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Detalhes bibliográficos
Main Authors: Zanin, Valentina, Marcuzzi, Annalisa, Kleiner, Giulio, Piscianz, Elisa, Monasta, Lorenzo, Zacchigna, Serena, Crovella, Sergio, Zauli, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838599/
https://ncbi.nlm.nih.gov/pubmed/23959762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-013-9506-8
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