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Pyrazoles as inhibitors of alcohol oxidation and as important tools in alcohol research: An approach to therapy against methanol poisoning

4-Methylpyrazole, in a dose producing inhibition of alcohol dehydrogenase (alcohol:NAD(+) oxidoreductase, EC 1.1.1.1), was given alone or together with ethanol (10%) as sole drinking fluid to growing rats for up to 38 weeks. Their weight curves remained normal. Electron microscopy of liver, kidney,...

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Detalhes bibliográficos
Main Authors: Blomstrand, Rolf, Östling-Wintzell, Helene, Löf, Agneta, McMartin, Kenneth, Tolf, Bo-Ragnar, Hedström, Karl-Göran
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC383854/
https://ncbi.nlm.nih.gov/pubmed/115004
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