Stimulation of GABA-Induced Ca(2+) Influx Enhances Maturation of Human Induced Pluripotent Stem Cell-Derived Neurons

Optimal use of patient-derived, induced pluripotent stem cells for modeling neuronal diseases is crucially dependent upon the proper physiological maturation of derived neurons. As a strategy to develop defined differentiation protocols that optimize electrophysiological function, we investigated th...

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Bibliografiske detaljer
Main Authors: Rushton, David J., Mattis, Virginia B., Svendsen, Clive N., Allen, Nicholas D., Kemp, Paul J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838360/
https://ncbi.nlm.nih.gov/pubmed/24278369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081031
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