New insights in extracellular matrix remodeling and collagen turnover related pathways in cultured human tenocytes after ciprofloxacin administration

We characterized the effect of ciprofloxacin (CPX) in cultured human tenocytes by morphological and molecular methods. Collagen type I and III mRNA and protein levels were unaffected, but lysyl hydroxylase 2b mRNA levels progressively decreased after CPX administration. MMP-1 protein levels signific...

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Bibliografski detalji
Glavni autori: Menon, Alessandra, Pettinari, Letizia, Martinelli, Carla, Colombo, Graziano, Portinaro, Nicola, Dalle-Donne, Isabella, d’Agostino, Maria Cristina, Gagliano, Nicoletta
Format: Artigo
Jezik:Inglês
Izdano: CIC Edizioni Internazionali 2013
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838320/
https://ncbi.nlm.nih.gov/pubmed/24367771
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