New insights in extracellular matrix remodeling and collagen turnover related pathways in cultured human tenocytes after ciprofloxacin administration

We characterized the effect of ciprofloxacin (CPX) in cultured human tenocytes by morphological and molecular methods. Collagen type I and III mRNA and protein levels were unaffected, but lysyl hydroxylase 2b mRNA levels progressively decreased after CPX administration. MMP-1 protein levels signific...

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Detalhes bibliográficos
Main Authors: Menon, Alessandra, Pettinari, Letizia, Martinelli, Carla, Colombo, Graziano, Portinaro, Nicola, Dalle-Donne, Isabella, d’Agostino, Maria Cristina, Gagliano, Nicoletta
Formato: Artigo
Idioma:Inglês
Publicado em: CIC Edizioni Internazionali 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838320/
https://ncbi.nlm.nih.gov/pubmed/24367771
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