Merkel Cell Polyomavirus Small T Antigen Targets the NEMO Adaptor Protein To Disrupt Inflammatory Signaling

Merkel cell carcinoma (MCC) is a highly aggressive nonmelanoma skin cancer arising from epidermal mechanoreceptor Merkel cells. In 2008, a novel human polyomavirus, Merkel cell polyomavirus (MCPyV), was identified and is strongly implicated in MCC pathogenesis. Currently, little is known regarding t...

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Autors principals: Griffiths, David A., Abdul-Sada, Hussein, Knight, Laura M., Jackson, Brian R., Richards, Kathryn, Prescott, Emma L., Peach, A. Howard S., Blair, G. Eric, Macdonald, Andrew, Whitehouse, Adrian
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838273/
https://ncbi.nlm.nih.gov/pubmed/24109239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02159-13
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