Merkel Cell Polyomavirus Small T Antigen Mediates Microtubule Destabilization To Promote Cell Motility and Migration

Merkel cell carcinoma (MCC) is an aggressive skin cancer of neuroendocrine origin with a high propensity for recurrence and metastasis. Merkel cell polyomavirus (MCPyV) causes the majority of MCC cases due to the expression of the MCPyV small and large tumor antigens (ST and LT, respectively). Altho...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Knight, Laura M., Stakaityte, Gabriele, Wood, Jennifer, J., Abdul-Sada, Hussein, Griffiths, David A., Howell, Gareth J., Wheat, Rachel, Blair, G. Eric, Steven, Neil M., Macdonald, Andrew, Blackbourn, David J., Whitehouse, Adrian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2014
Onderwerpen:
Virus-Cell Interactions
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301106/
https://ncbi.nlm.nih.gov/pubmed/25320307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02317-14
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