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Parvovirus B19 Uptake Is a Highly Selective Process Controlled by VP1u, a Novel Determinant of Viral Tropism

The VP1 unique region (VP1u) of human parvovirus B19 (B19V) is the immunodominant part of the viral capsid. Originally inaccessible, the VP1u becomes exposed upon primary attachment to the globoside receptor. To study the function of the exposed VP1u in B19V uptake, we expressed this region as a rec...

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Detalhes bibliográficos
Main Authors: Leisi, Remo, Ruprecht, Nico, Kempf, Christoph, Ros, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838272/
https://ncbi.nlm.nih.gov/pubmed/24067971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02548-13
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