Low pH-Dependent Endosomal Processing of the Incoming Parvovirus Minute Virus of Mice Virion Leads to Externalization of the VP1 N-Terminal Sequence (N-VP1), N-VP2 Cleavage, and Uncoating of the Full-Length Genome

Minute virus of mice (MVM) enters the host cell via receptor-mediated endocytosis. Although endosomal processing is required, its role remains uncertain. In particular, the effect of low endosomal pH on capsid configuration and nuclear delivery of the viral genome is unclear. We have followed the pr...

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Bibliografiske detaljer
Main Authors: Mani, Bernhard, Baltzer, Claudia, Valle, Noelia, Almendral, José M., Kempf, Christoph, Ros, Carlos
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346861/
https://ncbi.nlm.nih.gov/pubmed/16379002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.1015-1024.2006
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