Efficiency of Cell-Free and Cell-Associated Virus in Mucosal Transmission of Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus

Effective strategies are needed to block mucosal transmission of human immunodeficiency virus type 1 (HIV-1). Here, we address a crucial question in HIV-1 pathogenesis: whether infected donor mononuclear cells or cell-free virus plays the more important role in initiating mucosal infection by HIV-1....

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Detalhes bibliográficos
Main Authors: Kolodkin-Gal, Dror, Hulot, Sandrine L., Korioth-Schmitz, Birgit, Gombos, Randi B., Zheng, Yi, Owuor, Joshua, Lifton, Michelle A., Ayeni, Christian, Najarian, Robert M., Yeh, Wendy W., Asmal, Mohammed, Zamir, Gideon, Letvin, Norman L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838232/
https://ncbi.nlm.nih.gov/pubmed/24109227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03108-12
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