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Kaposi's Sarcoma-Associated Herpesvirus Transactivator Rta Induces Cell Cycle Arrest in G(0)/G(1) Phase by Stabilizing and Promoting Nuclear Localization of p27(kip)
The Kaposi's sarcoma-associated herpesvirus (KSHV) immediate-early gene, replication, and transcription activator (K-Rta) is a key viral protein that serves as the master regulator for viral lytic replication. In this study, we investigated the role of K-Rta in cell cycle regulation and found t...
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Format: | Artigo |
Jezik: | Inglês |
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American Society for Microbiology
2013
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838229/ https://ncbi.nlm.nih.gov/pubmed/24067984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02540-13 |
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