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Kaposi's Sarcoma-Associated Herpesvirus Transactivator Rta Induces Cell Cycle Arrest in G(0)/G(1) Phase by Stabilizing and Promoting Nuclear Localization of p27(kip)

The Kaposi's sarcoma-associated herpesvirus (KSHV) immediate-early gene, replication, and transcription activator (K-Rta) is a key viral protein that serves as the master regulator for viral lytic replication. In this study, we investigated the role of K-Rta in cell cycle regulation and found t...

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Detalhes bibliográficos
Main Authors: Kumar, Pankaj, Wood, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838229/
https://ncbi.nlm.nih.gov/pubmed/24067984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02540-13
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