The Viral Ubiquitin Ligase ICP0 Is neither Sufficient nor Necessary for Degradation of the Cellular DNA Sensor IFI16 during Herpes Simplex Virus 1 Infection

The cellular protein IFI16 colocalizes with the herpes simplex virus 1 (HSV-1) ubiquitin ligase ICP0 at early times of infection and is degraded as infection progresses. Here, we report that the factors governing the degradation of IFI16 and its colocalization with ICP0 are distinct from those of pr...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cuchet-Lourenço, Delphine, Anderson, Gail, Sloan, Elizabeth, Orr, Anne, Everett, Roger D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2013
Gaiak:
Virus-Cell Interactions
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838218/
https://ncbi.nlm.nih.gov/pubmed/24089555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02474-13
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