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CEACAM-1 negatively regulates G-CSF production by breast tumor associated macrophages that mediate tumor angiogenesis

CEACAM1, a cell adhesion molecule expressed on epithelial cells and activated immune cells, is down-regulated in many cancers and plays a role in inhibition of inflammation in part by inhibition of G-CSF production by myeloid cells. Since macrophages are associated with a poor prognosis in breast ca...

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Bibliografiske detaljer
Main Authors: Samieni, Sridhar, Zhang, Zhifang, Shively, John E.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838202/
https://ncbi.nlm.nih.gov/pubmed/23319418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28036
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