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Epigenetic mechanisms and developmental choice hierarchies in T-lymphocyte development

Three interlocking problems in gene regulation are: how to explain genome-wide targeting of transcription factors in different cell types, how prior transcription factor action can establish an ‘epigenetic state’ that changes the options for future transcription factor action, and how directly a seq...

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Autor principal: Rothenberg, Ellen V.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838197/
https://ncbi.nlm.nih.gov/pubmed/23922132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bfgp/elt027
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