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Epigenetic mechanisms and developmental choice hierarchies in T-lymphocyte development
Three interlocking problems in gene regulation are: how to explain genome-wide targeting of transcription factors in different cell types, how prior transcription factor action can establish an ‘epigenetic state’ that changes the options for future transcription factor action, and how directly a seq...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2013
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838197/ https://ncbi.nlm.nih.gov/pubmed/23922132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bfgp/elt027 |
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