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A Novel Role for Keratin 17 in Coordinating Oncogenic Transformation and Cellular Adhesion in Ewing Sarcoma

Oncogenic transformation in Ewing sarcoma is caused by EWS/FLI, an aberrant transcription factor fusion oncogene. Glioma-associated oncogene homolog 1 (GLI1) is a critical target gene activated by EWS/FLI, but the mechanism by which GLI1 contributes to the transformed phenotype of Ewing sarcoma was...

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Autors principals: Sankar, Savita, Tanner, Jason M., Bell, Russell, Chaturvedi, Aashi, Randall, R. Lor, Beckerle, Mary C., Lessnick, Stephen L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838177/
https://ncbi.nlm.nih.gov/pubmed/24043308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00241-13
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