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Cell Cycle Deregulation in Ewing's Sarcoma Pathogenesis
Ewing's sarcoma is a highly aggressive pediatric tumor of bone that usually contains the characteristic chromosomal translocation t(11;22)(q24;q12). This translocation encodes the oncogenic fusion protein EWS/FLI, which acts as an aberrant transcription factor to deregulate target genes necessa...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2968116/ https://ncbi.nlm.nih.gov/pubmed/21052502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/598704 |
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