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Phosphorylation of Rac1 T108 by Extracellular Signal-Regulated Kinase in Response to Epidermal Growth Factor: a Novel Mechanism To Regulate Rac1 Function

Accumulating evidence has implicated Rho GTPases, including Rac1, in many aspects of cancer development. Recent findings suggest that phosphorylation might further contribute to the tight regulation of Rho GTPases. Interestingly, sequence analysis of Rac1 shows that Rac1 T108 within the (106)PNTP(10...

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Библиографические подробности
Главные авторы: Tong, Junfeng, Li, Laiji, Ballermann, Barbara, Wang, Zhixiang
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838176/
https://ncbi.nlm.nih.gov/pubmed/24043306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00822-13
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