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MEF2 Is a Converging Hub for Histone Deacetylase 4 and Phosphatidylinositol 3-Kinase/Akt-Induced Transformation

The MEF2-class IIa histone deacetylase (HDAC) axis operates in several differentiation pathways and in numerous adaptive responses. We show here that nuclear active HDAC4 and HDAC7 display transforming capability. HDAC4 oncogenic potential depends on the repression of a limited set of genes, most of...

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Main Authors: Di Giorgio, Eros, Clocchiatti, Andrea, Piccinin, Sara, Sgorbissa, Andrea, Viviani, Giulia, Peruzzo, Paolo, Romeo, Salvatore, Rossi, Sabrina, Dei Tos, Angelo Paolo, Maestro, Roberta, Brancolini, Claudio
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838174/
https://ncbi.nlm.nih.gov/pubmed/24043307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01050-13
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