MEF2 Is a Converging Hub for Histone Deacetylase 4 and Phosphatidylinositol 3-Kinase/Akt-Induced Transformation

The MEF2-class IIa histone deacetylase (HDAC) axis operates in several differentiation pathways and in numerous adaptive responses. We show here that nuclear active HDAC4 and HDAC7 display transforming capability. HDAC4 oncogenic potential depends on the repression of a limited set of genes, most of...

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Main Authors: Di Giorgio, Eros, Clocchiatti, Andrea, Piccinin, Sara, Sgorbissa, Andrea, Viviani, Giulia, Peruzzo, Paolo, Romeo, Salvatore, Rossi, Sabrina, Dei Tos, Angelo Paolo, Maestro, Roberta, Brancolini, Claudio
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838174/
https://ncbi.nlm.nih.gov/pubmed/24043307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01050-13
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