High-Avidity and Potently Neutralizing Cross-Reactive Human Monoclonal Antibodies Derived from Secondary Dengue Virus Infection

The envelope (E) protein of dengue virus (DENV) is the major target of neutralizing antibodies (Abs) and vaccine development. Previous studies of human dengue-immune sera reported that a significant proportion of anti-E Abs, known as group-reactive (GR) Abs, were cross-reactive to all four DENV sero...

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Detalhes bibliográficos
Main Authors: Tsai, Wen-Yang, Lai, Chih-Yun, Wu, Yi-Chieh, Lin, Hong-En, Edwards, Carolyn, Jumnainsong, Amonrat, Kliks, Srisakul, Halstead, Scott, Mongkolsapaya, Juthathip, Screaton, Gavin R., Wang, Wei-Kung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838129/
https://ncbi.nlm.nih.gov/pubmed/24027331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00871-13
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