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Bromo- and Extraterminal Domain Chromatin Regulators Serve as Cofactors for Murine Leukemia Virus Integration

Retroviral integrase (IN) proteins catalyze the permanent integration of proviral genomes into host DNA with the help of cellular cofactors. Lens epithelium-derived growth factor (LEDGF) is a cofactor for lentiviruses, including human immunodeficiency virus type 1 (HIV-1), and targets lentiviral int...

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Detalhes bibliográficos
Main Authors: Gupta, Saumya Shree, Maetzig, Tobias, Maertens, Goedele N., Sharif, Azar, Rothe, Michael, Weidner-Glunde, Magdalena, Galla, Melanie, Schambach, Axel, Cherepanov, Peter, Schulz, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838128/
https://ncbi.nlm.nih.gov/pubmed/24049186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01942-13
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