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Baculovirus F-Box Protein LEF-7 Modifies the Host DNA Damage Response To Enhance Virus Multiplication

The DNA damage response (DDR) of a host organism represents an effective antiviral defense that is frequently manipulated and exploited by viruses to promote multiplication. We report here that the large DNA baculoviruses, which require host DDR activation for optimal replication, encode a conserved...

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Autors principals: Mitchell, Jonathan K., Byers, Nathaniel M., Friesen, Paul D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838121/
https://ncbi.nlm.nih.gov/pubmed/24027328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02501-13
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