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Baculovirus Inhibitor-of-Apoptosis Op-IAP3 Blocks Apoptosis by Interaction with and Stabilization of a Host Insect Cellular IAP

Baculovirus-encoded inhibitor of apoptosis (IAP) proteins likely evolved from their host cell IAP homologs, which function as critical regulators of cell death. Despite their striking relatedness to cellular IAPs, including the conservation of two baculovirus IAP repeat (BIR) domains and a C-termina...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Byers, Nathaniel M., Vandergaast, Rianna L., Friesen, Paul D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702543/
https://ncbi.nlm.nih.gov/pubmed/26491164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02320-15
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