B Cell Activating Factor Inhibition Impairs Bacterial Immunity by Reducing T Cell-Independent IgM Secretion

B cell activating factor of the tumor necrosis factor family (BAFF) is an essential survival factor for B cells and has been shown to regulate T cell-independent (TI) IgM production. During Ehrlichia muris infection, TI IgM secretion in the spleen was BAFF dependent, and antibody-mediated BAFF neutr...

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Bibliografiske detaljer
Main Authors: Jones, Derek D., Jones, Maura, DeIulio, Gregory A., Racine, Rachael, MacNamara, Katherine C., Winslow, Gary M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837985/
https://ncbi.nlm.nih.gov/pubmed/24082070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00998-13
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