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Impaired Innate Mucosal Immunity in Aged Mice Permits Prolonged Streptococcus pneumoniae Colonization

Streptococcus pneumoniae is a frequent asymptomatic colonizer of the nasopharyngeal niche and only occasionally progresses toward infection. The burden of pneumococcal disease is particularly high in the elderly, and the mechanisms behind this increased susceptibility are poorly understood. Here we...

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Bibliographic Details
Main Authors: Krone, Cassandra L., Trzciński, Krzysztof, Zborowski, Tomasz, Sanders, Elisabeth A. M., Bogaert, Debby
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837976/
https://ncbi.nlm.nih.gov/pubmed/24082075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00618-13
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