Genotypic Analysis of the V3 Region of HIV from Virologic Nonresponders to Maraviroc-Containing Regimens Reveals Distinct Patterns of Failure

Changes in HIV tropism from R5 to non-R5 or development of drug resistance is often associated with virologic failure in patients treated with maraviroc, a CCR5 antagonist. We sought to examine changes in HIV envelope sequences and inferred tropism in patients who did not respond to maraviroc-based...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Swenson, Luke C., Chui, Celia K. S., Brumme, Chanson J., Chan, Dennison, Woods, Conan K., Mo, Theresa, Dong, Winnie, Chapman, Doug, Lewis, Marilyn, Demarest, James F., James, Ian, Portsmouth, Simon, Goodrich, James, Heera, Jayvant, Valdez, Hernan, Harrigan, P. Richard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2013
Aiheet:
Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837924/
https://ncbi.nlm.nih.gov/pubmed/24080655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01534-13
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