Genotypic Analysis of the V3 Region of HIV from Virologic Nonresponders to Maraviroc-Containing Regimens Reveals Distinct Patterns of Failure

Changes in HIV tropism from R5 to non-R5 or development of drug resistance is often associated with virologic failure in patients treated with maraviroc, a CCR5 antagonist. We sought to examine changes in HIV envelope sequences and inferred tropism in patients who did not respond to maraviroc-based...

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Detalhes bibliográficos
Main Authors: Swenson, Luke C., Chui, Celia K. S., Brumme, Chanson J., Chan, Dennison, Woods, Conan K., Mo, Theresa, Dong, Winnie, Chapman, Doug, Lewis, Marilyn, Demarest, James F., James, Ian, Portsmouth, Simon, Goodrich, James, Heera, Jayvant, Valdez, Hernan, Harrigan, P. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837924/
https://ncbi.nlm.nih.gov/pubmed/24080655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01534-13
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