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Protein Binding of β-Lactam Antibiotics in Critically Ill Patients: Can We Successfully Predict Unbound Concentrations?

The use of therapeutic drug monitoring (TDM) to optimize beta-lactam dosing in critically ill patients is growing in popularity, although there are limited data describing the potential impact of altered protein binding on achievement of target concentrations. The aim of this study was to compare th...

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Detalhes bibliográficos
Main Authors: Wong, Gloria, Briscoe, Scott, Adnan, Syamhanin, McWhinney, Brett, Ungerer, Jacobus, Lipman, Jeffrey, Roberts, Jason A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837907/
https://ncbi.nlm.nih.gov/pubmed/24080664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00951-13
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