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One-Month Transplacental Pharmacokinetics of Raltegravir in a Premature Newborn after Short-Course Treatment of the HIV-1-Infected Mother

We describe the pharmacokinetics of raltegravir of a preterm newborn after short-course treatment of the mother tested HIV + the day of delivery. At age 1 month, the circulating concentration of raltegravir in the newborn was 29 ng/ml (the IC95 of RAL against HIV-1 is 15 ng/ml). Raltegravir should t...

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Hlavní autoři: Clavel-Osorio, C., Cazassus, F., Stegmann, S., Huc-Anaïs, P., Lecam, D., Peytavin, G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837897/
https://ncbi.nlm.nih.gov/pubmed/24080650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01349-13
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