In Vitro Characterization of PlySK1249, a Novel Phage Lysin, and Assessment of Its Antibacterial Activity in a Mouse Model of Streptococcus agalactiae Bacteremia

Beta-hemolytic Streptococcus agalactiae is the leading cause of bacteremia and invasive infections. These diseases are treated with β-lactams or macrolides, but the emergence of less susceptible and even fully resistant strains is a cause for concern. New bacteriophage lysins could be promising alte...

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Bibliographic Details
Main Authors: Oechslin, Frank, Daraspe, Jean, Giddey, Marlyse, Moreillon, Philippe, Resch, Grégory
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837886/
https://ncbi.nlm.nih.gov/pubmed/24100496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01701-13
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