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Antifungal Prophylaxis with Posaconazole in Patients with Acute Myeloid Leukemia: Dose Intensification Coupled with Avoidance of Proton Pump Inhibitors Is Beneficial in Shortening Time to Effective Concentrations

This study aimed to assess the influence of dose frequency and the presence or absence of cotreatment with proton pump inhibitors (PPIs) on the time to a target trough concentration (C(min)) of >700 ng/ml with posaconazole in the first 8 days of antifungal prophylaxis in hematological patients. T...

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Bibliografski detalji
Glavni autori: Cojutti, Piergiorgio, Candoni, Anna, Simeone, Erica, Franceschi, Loretta, Fanin, Renato, Pea, Federico
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837868/
https://ncbi.nlm.nih.gov/pubmed/24060872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01586-13
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