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Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput Assay

The design of new antimalarial combinations to treat Plasmodium falciparum infections requires drugs that, in addition to resolving disease symptoms caused by asexual blood stage parasites, can also interrupt transmission to the mosquito vector. Gametocytes, which are essential for transmission, dev...

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Autores principales: Lucantoni, Leonardo, Duffy, Sandra, Adjalley, Sophie H., Fidock, David A., Avery, Vicky M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837862/
https://ncbi.nlm.nih.gov/pubmed/24060871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00870-13
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