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Pharmacokinetic and Pharmacodynamic Considerations in Antimalarial Dose Optimization
Antimalarial drugs have usually been first deployed in areas of malaria endemicity at doses which were too low, particularly for high-risk groups such as young children and pregnant women. This may accelerate the emergence and spread of resistance, thereby shortening the useful life of the drug, but...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837842/ https://ncbi.nlm.nih.gov/pubmed/24002099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00287-13 |
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