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Pharmacokinetic and Pharmacodynamic Considerations in Antimalarial Dose Optimization

Antimalarial drugs have usually been first deployed in areas of malaria endemicity at doses which were too low, particularly for high-risk groups such as young children and pregnant women. This may accelerate the emergence and spread of resistance, thereby shortening the useful life of the drug, but...

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Autore principale: White, Nicholas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837842/
https://ncbi.nlm.nih.gov/pubmed/24002099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00287-13
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