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Evolved Cobalamin-Independent Methionine Synthase (MetE) Improves the Acetate and Thermal Tolerance of Escherichia coli

Acetate-mediated growth inhibition of Escherichia coli has been found to be a consequence of the accumulation of homocysteine, the substrate of the cobalamin-independent methionine synthase (MetE) that catalyzes the final step of methionine biosynthesis. To improve the acetate resistance of E. coli,...

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Autors principals: Mordukhova, Elena A., Pan, Jae-Gu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837807/
https://ncbi.nlm.nih.gov/pubmed/24123739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01952-13
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