The Hemopexin Domain of Matrix Metalloproteinase-9 Activates Cell Signaling and Promotes Migration of Schwann Cells by Binding to Low-Density Lipoprotein Receptor-Related Protein

Low-density lipoprotein receptor-related protein (LRP-1) is an endocytic receptor for diverse proteins, including matrix metalloproteinase-9 (MMP-9), and a cell-signaling receptor. In the peripheral nervous system (PNS), LRP-1 is robustly expressed by Schwann cells only after injury. Herein, we demo...

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Autori principali: Mantuano, Elisabetta, Inoue, Gen, Li, Xiaoqing, Takahashi, Kazuhisa, Gaultier, Alban, Gonias, Steven L., Campana, W. Marie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837707/
https://ncbi.nlm.nih.gov/pubmed/18987193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3053-08.2008
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